Heck reaction of arenediazonium salts with N,N-diprotected allylamines. Synthesis of cinnamylamines and indoles.

نویسندگان

  • Sandro Cacchi
  • Giancarlo Fabrizi
  • Antonella Goggiamani
  • Alessio Sferrazza
چکیده

Novel palladium-catalyzed reactions of arenediazonium tetrafluoroborates with N,N-diprotected allylamines are presented. The reaction of arenediazonium tetrafluoroborates with N,N-(Boc)(2) allylamine allows for an easy approach to cinnamylamines whereas using 2-alkynyl-N-(allyl)trifluoroacetanilides and 2-iodo-N-(allyl)trifluoroacetanilide the reaction provides a useful tool for appending indole rings to aniline fragments.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 9 6  شماره 

صفحات  -

تاریخ انتشار 2011